Bayer Schering Pharma AG, Germany owns Alka-Seltzer, which was launched in 1931 and was meant for relief of minor aches, pains, inflammation, fever, headache, heartburn, sour stomach, indigestion, and hangovers.

Bayer Schering Pharma AG, Germany owns Alka-Seltzer, which was launched in 1931 and was meant for relief of minor aches, pains, inflammation, fever, headache, heartburn, sour stomach, indigestion, and hangovers. Alka-Seltzer Plus was a spin-off of the original medicine, meant to relieve colds and flu. The company has recently introduced a new and improved Alka-Seltzer Plus, as described in this TV ad. The ad shows that Alka-Seltzer Plus can fight congestion, unlike NyQuil. Explain how Alka-Seltzer Plus has been quality and price-positioned in an existing market. In your opinion, has Bayer positioned their product appropriately in the market for cold and flu symptoms relief products? Would you advise Bayer to use a skimming or a penetration pricing strategy? Explain your reasoning. How do you think Proctor and Gamble, the company who produces Vicks NyQuil, would respond to the ad?

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

Tom and Marie are thinking of opening a fitness centre with facilities for aerobics, weight training, jogging and lap swimming, as well as diet and injury consultation.

Tom and Marie are thinking of opening a fitness centre with facilities for aerobics, weight training, jogging and lap swimming, as well as diet and injury consultation. They plan to buy land and build their facility near the new shopping centre. They want to employ a director, an assistant director, experts to supervise members in each fitness area, and numerous consulting dietitians and sports medicine professionals. They hope to have the entire facility, including an outdoor all-weather track and an indoor swimming pool, completed by the end of the year. They also believe that it will be important to have the facility fully equipped and staffed before they begin taking memberships. Although their estimates indicate that the fitness centre can be profitable if they can establish a growing membership over the first five or six years, many small businesses in town have failed because of ‘cash flow problems’ (excess of cash payments over cash receipts). Before committing themselves to this venture, Tom and Marie have come to you for advice and for help in preparing a cash budget.Required: Write Tom and Marie a memo explaining why they might have cash flow problems during their early periods of operations. Show them how they can identify these cash flow problems through careful cash budgeting. Make a few suggestions that might help them reduce such problems if they do decide to open the fitness centre.

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

Advanced Bio Medics (ABM) has invented a new stem-cell–based drug that will arrest even advanced forms of lung cancer.

Advanced Bio Medics (ABM) has invented a new stem-cell–based drug that will arrest even advanced forms of lung cancer. Development costs were actually quite low because the drug was an accidental discovery by scientists working on a different project. To stop the disease requires a regimen of one pill per week for 20 weeks. There is no substitute offered by competitors. ABM is thinking that it could maximize its profits by charging $10,000 per pill. Of course, many people will die because they can’t afford the medicine at this price.What pricing strategy is ABM using? Read the following current story What’s a fair price for a drug? (http://www.bbc.com/news/health-34322720) which is a real life illustration of this strategy. Do you feel this is an appropriate pricing strategy for these products? Discuss the ethics of ABM’s and Shkreli’s strategies. Do you think they will be successful? What are the ramifications of the high price? What would you recommend if you were deciding on the price for this product? What would you have to consider when making your decision? Support your answer.

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

Probably the most important source of capital is human capital

Probably the most important source of capital is human capital. For example, most medical doctors spend years learning to practice medicine. Doctors are willing to make large investments in their human capital because they expect to be compensated for doing so when they begin work. In Canada, the government nationalized the healthcare system and reduced doctors’ compensation. Is this a form of post-investment hold-up?

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

The demand for a new drug is given by equation Q = 150 – 3P (where Q is the bottles of medicine and P is the price per bottle in dollars).

The demand for a new drug is given by equation Q = 150 – 3P (where Q is the bottles of medicine and P is the price per bottle in dollars). The slope of the demand curve is -1/3.What is the equation for total revenue iin terms of Q?1) TR = 50Q – 3Q22) TR = 150Q – 3PQ3) TR = 50Q – Q2/34) TR = 50Q2 – Q/35) TR = 150 – 3Q2What is the equation for marginal revenue?1) MR = 50 – (1/3)Q2) MR = 150 – (2/3)Q3) MR = 150 – 6Q4) MR = 150 – 6P5) MR = 50 – (2/3)Q

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

Write a case summary and solutionTIM CALKINSForecasting Denosumab“Our job is quite simple,” explained Jennifer Fry, project manager at Oakdale StrategyGroup, a strategy consulting firm based in Chicago

Write a case summary and solutionTIM CALKINSForecasting Denosumab“Our job is quite simple,” explained Jennifer Fry, project manager at Oakdale StrategyGroup, a strategy consulting firm based in Chicago. It was a cold day in early February 2011, andFry was meeting with her team. “We’ve been asked to develop a forecast for denosumab for2015,” she continued. “Our client is one of the world’s largest pharmaceutical firms. The seniorexecutives there are taking a close look at acquiring Amgen and want an outside opinion aboutdenosumab.”Steven Meyers, a partner at the firm, quickly jumped in. “This is an incredibly high-profileassignment because the value of Amgen is closely tied to the revenue forecast for denosumab.We’ve got an important client and a very important project. Let’s nail this one.”AmgenAmgen was one of the world’s leading biotechnology companies, with more than 17,000employees and almost $15 billion in revenue. The company was founded in 1980 under the nameApplied Molecular Genetics and assumed the name Amgen in 1983.Amgen was highly profitable; in 2009 it had net income of $4.6 billion on revenues of $14.6billion (see Exhibit 1).In 2010 Amgen had ten drugs approved for sales in the United States. The most important ofthese were Aranesp and Epogen, for anemia; Enbrel, for arthritis; and Neulasta, for febrileneutropenia, a condition associated with chemotherapy (see Exhibit 2).Despite its considerable success, Amgen was in a difficult position in 2011; the company’score products were not growing and Aranesp was declining sharply. In addition, patent expirationissues loomed. As a result, Amgen’s stock was not performing well; it had peaked in 2005 atmore than $85 per share but had declined to about $55 per share five years later.Amgen’smost promising new product was denosumab, a fully human monoclonal antibodydesigned to treat osteoporosis. Amgen began working on the molecule in 1994 and finallylaunched it sixteen years later under the brand names Prolia and Xgeva. As CEO Kevin Sharerwrote in Amgen’s 2009 annual report, “Doctors and experts who have reviewed the data are©2011 by the Kellogg School of Management at Northwestern University. This case was prepared by Professor Tim Calkins andNayna Aggarwal ’12. Cases are developed solely as the basis for class discussion. Although the product discussed in this case is real,the specific characters and scenario are fictional. Cases are not intended to serve as endorsements, sources of primary data, orillustrations of effective or ineffective management. To order copies or request permission to reproduce materials, call 800-545-7685(or 617-783-7600 outside the United States or Canada) or e-mail custserv@hbsp.harvard.edu. No part of this publication may bereproduced, stored in a retrieval system, used in a spreadsheet, or transmitted in any form or by any means—electronic, mechanical,photocopying, recording, or otherwise—without the permission of the Kellogg School of Management.This document is authorized for use only by Rudy Nunez in Cases in Operations Management-1 taught by Cheng Li, from January 2016 to July 2016.For the exclusive use of R. Nunez, 2016.FORECASTING DENOSUMAB KEL531excited and optimistic that this twice-a-year injection could bring new hope and benefit to largenumbers of patients.”1Amgen had patents on denosumab that were scheduled to expire between 2017 and 2023.OsteoporosisOsteoporosis, a bone disorder, was a common but serious condition. According to theNational Osteoporosis Foundation:Osteoporosis is a condition in which the bones become weak and can break more easily.In serious cases, something as simple as a sneeze can cause a bone to break. About 10million Americans already have the disease. About 34 million are at risk. Being at riskfor osteoporosis means you are more likely to get the disease. Estimates suggest thatabout half of all women older than 50 will break a bone because of osteoporosis. Up toone in four men will too.2Bones are constantly changing: cells called osteoblasts create new bone, while those knownas osteoclasts break down old bone. In young people, bone is created faster than it is brokendown, so bone mass increases and bones strengthen. In older people, however, this balance isreversed. Bone strength generally peaks at about the age of 30. As bones weaken with age, peopledevelop osteopenia, a reduction in bone mass. If the process continues, people developosteoporosis.Osteopenia and osteoporosis can occur at any age, but it is most common among people olderthan 50. Women are four times more likely than men to develop osteoporosis. As a woman’slevels of the hormone estrogen declines (such as during menopause), her risk of bone losssignificantly increases.With no obvious symptoms, osteopenia and osteoporosis often go undetected until adiagnosis from a healthcare professional. Untreated, a person can continue living withosteoporosis for many years. The risk of a fracture during this time, however, increasessignificantly.Fractures are a significant issue for older people. One study of postmenopausal women withosteoporosis reported that 10.9 percent had a vertebral fracture and 2.5 percent had a hip fractureduring a three-year period.3The main way to diagnose osteoporosis was with a bone mineral density (BMD) test. Theprimary BMD test was dual-energy X-ray absorptiometry (DXA). During a measurement processthat generally took between ten and twenty minutes, a DXA scanner produced two X-ray beamswith different levels of energy. The machine tracked the amount of energy that passed through thebone.Amgen 2009 Annual Report, p. 1.1National Osteoporosis Foundation, “Why Bone Health Is Important,” http://www.nof.org/node/150. 32Murray J. Favus, “Bisphosphonates for Osteoporosis,” New England Journal of Medicine 363 (2010): 2029.2 KELLOGG SCHOOL OF MANAGEMENTThis document is authorized for use only by Rudy Nunez in Cases in Operations Management-1 taught by Cheng Li, from January 2016 to July 2016.For the exclusive use of R. Nunez, 2016.KEL531 FORECASTING DENOSUMABThe DXA scanner produced a T-score, a statistic used to measure bone density that compareda patient’s BMD to that of a 30-year-old. The risk of fractures increased significantly with lowerT-scores. A normal T-score was -1.0 or higher; osteopenia was defined by a score of -1.0 to -2.5;and osteoporosis produced a score of -2.5 or lower.Osteoporosis Treatment OptionsSeveral treatment options were available for patients with osteopenia and osteoporosis (seeExhibits 3 and 4).EXERCISEStudies had shown that exercise strengthens bones. Young people who exercise achieve agreater peak bone mass, and older people who exercise slow the progress of bone erosion. Themost important exercises for bone strength were weight bearing, such as walking, jogging, stairclimbing, and weight lifting.DIETARY SUPPLEMENTSMany physicians recommended that people at risk for osteopenia take calcium and vitamin Dsupplements to maintain bone health.BISPHOSPHONATESThe main class of drugs for the treatment of osteopenia and osteoporosis in early 2011 wasbisphosphonates, made from two phosphonic groups. The drugs worked by slowing thebreakdown of bone by osteoclasts, resulting in an increase in BMD and a decrease in fractures.Studies on bisphosphonates had consistently shown that the products were effective atincreasing BMD and at reducing fractures. In clinical trials, most of the products demonstrated a40 to 50 percent reduction in vertebral fractures.Side effects generally were moderate. Some patients complained of an upset stomach whentaking an oral bisphosphonate; this was the most common side effect. Some studies showed thatabout 25 percent of patients experience at least mild gastrointestinal side effects. However, in astudy of the leading bisphosphonate, only 6.6 percent of patients complained of abdominal pain,compared to 4.1 percent of patients taking a placebo.4osteonecrosis (or decaying) of the jaw, a serious side effect. In addition, questions arose in thefield regarding the long-term use of the products, with an unusual number of fractures amongpatients who had used bisphosphonates for many years. Some scientists believed this class ofdrugs suppressed bone turnover, which led to fractures after years of use.Despite the strong efficacy of bisphosphonates, compliance was low; studies indicated thatabout 50 percent of patients discontinued oral bisphosphonate therapy within the first year. Thehigh discontinuance rate was likely due to the absence of readily visible benefits and to thepresence of gastrointestinal side effects in some patients. In addition, most bisphosphonates werepatient-administered, not physician-administered, which contributed to low compliance.

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

The CEO of St. Sebastian Health System, a moderate-sized hospital system in a mid-sized, Midwest city has hired you to help turn things around.

The CEO of St. Sebastian Health System, a moderate-sized hospital system in a mid-sized, Midwest city has hired you to help turn things around. The CFO is projecting a $3.7 million operating loss this year, which will be more than offset by non-operating income. However, the board has made it clear that the situation must improve. If the system cannot produce a positive operating margin in 2017, someone else is going to be the CEO. The CEO and CFO have asked you to recommend strategic approaches to selling their services in the community that will help turn the financial ship around.Your Health SystemSt. Sebastian is a community-based health system. The senior management team has an average tenure of 17 years. The exception is the Chief Medical Officer (CMO). She has been in her position for two years and is the fourth CMO in that role in the past ten years. The CEO and COO have each been in their current roles for ten years. The system is comprised of the following:Two large, acute care hospitalsTwo long term care facilitiesTwo skilled nursing facilitiesOne long-term acute-care hospital (LTAC)Four geographically distributed outpatient centersFour Urgent Care CentersTwo free-standing ambulatory surgery centers (ASCs)A 400 member employed physician group that includes 180 Primary Care Providers (PCPs). All 28PCP practices are certified Level III Patient Centered Medical Homes by NCQA.The remainder of the 1,000 member medical staff is generally comprised of large, independent groups who have varying degrees of ‘loyalty’ to the system. The Radiology and Emergency groups, for example do 100% of their work at St. Sebastian and have no ownership of any outside facilities. The Gastroenterology group, on the other hand, does work at the hospital, but also owns their own, freestanding endoscopy center. The orthopedic group does 75% of their work at St. Sebastian, but maintains privileges at other facilities. They do not own their own ASC.In the current year, St. Sebastian is projecting 220,000 patient visits (combined IP and OP) with an average cost per visit of $1,727. They have an average charge per visit of $4,545.Over the past ten years, St. Sebastian has been active in pursuing a number of different strategic projects including:They have established ‘clinical institutes’ in cardiovascular, orthopedic, oncology, maternity and neurologic care. Each of these has been built through a co-management agreement between the system and the internal or external physician group who would be most logical. Each institute is led by a dyad of an administrator and medical director.Five years ago, they consolidated maternity programs to one facility, a move that justified investing in a Level III Neonatal Intensive Care Unit (NICU)They have established a research division in the hopes of working with national pharmaceutical companies and/or tertiary care hospitals in the Midwest.They have established a Physician Hospital Organization (PHO) and intend to become an Accountable Care Organization (ACO) that can participate in the Medicare Shared SavingsProgram (MSSP) and/or enter into global risk contracts with third party payers. The PHO is currently evaluating whether or not they should purchase an insurance license so that they could offer commercial, Medicare Advantage and Managed Medicaid insurance products.5. They have established a Business Health division to service the corporate health needs of the employers in the region. This would include things like EAP programs, on-site wellness, drug screening, on-site clinics, etc. This division also recently built two large, full-service fitness centers.The competition – The community is currently served by three other major health providers:Mercy is the competitor acute care system in town and has two hospitals and various outpatient centers. They have not been active in physician employment – they employ a group of 60 PCPs, but no specialists. Similarly, they have not been engaged in ‘branching out’ with different strategic initiatives, preferring instead to focus on cost efficient care. They do not have clinical institutes, research divisions, a PHO or a Business Health division. They have 230,000 visits per year, with an average cost of $1,435 per visit and an average charge of $4,348.General Pediatric is a pediatric teaching hospital. Five years ago, they signed an affiliation agreement with Johns Hopkins to gain access to clinical and research capabilities that would have been beyond their reach, given their size. They employee essentially all of the pediatric subspecialists and have a PHO, which includes 75% of the region’s primary care pediatricians. They will have 200,000 visits this year, with an average cost of $2,100 per visit and an average charge of $5,000 per visit.General University is an adult teaching hospital affiliated with the local university’s medical school. They staff the region’s free-care clinics and historically, have been the region’s hospital for indigent/uninsured patients. They are the region’s Level I trauma center and are well regarded for intensive services like trauma, stroke and cancer care. However, their location and reputation for taking indigent patients means that they are not preferred for ‘normal’ medical care by commercially insured or Medicare patients. Besides the community health centers, they own an inpatient rehab hospital, but not other facilities. They have explored affiliations with national leaders in academic medicine, but so far have not signed any such agreements. They see 180,000 visits per year with an average cost of $1,833 and an average charge of $5,556 per visit.There are no other hospitals currently operating, though there are 23 skilled nursing facilities (SNFs) and 3 inpatient rehab facilities throughout the region. They are independent actors and for the most part are struggling to stay profitable. There are several single-specialty physician groups who operate ambulatory surgery centers and one chain of independent diagnostic treatment facilities (IDTFs). Three years ago, there was a significant change in the state government, and that resulted in the long-time Certificate of Need (CON) program being all but scrapped (Skilled Nursing Facilities are still heavily regulated). Several for-profit hospital companies have recently done some analysis around entering your market, but have not done so yet.The Community – The community is a Midwest city and surrounding suburbs in the midst of a transition from a manufacturing employment base, which unfortunately accelerated with the 2008 economic downturn. The hospitals have seen this over the past several years in a tightening of benefits offered by local employers. Benefits continue to be offered, but increasingly are likely to have a significant deductible associated with them. Unemployment has been above the national average and is projectedto remain that way. This means that the average wage in the region is actually below where it was in 2008, when the last recession hit. The number of Medicare-age residents are projected to rise over the next 10-20 years, while working age patients are projected to stay flat or fall slightly. Similarly, birth rates are expected to fall slightly over the coming decade.The community is 60 miles south, 45 miles east and 50 miles north of other, similarly sized cities. Until 20 years ago, that made this city effectively an island unto itself. Increasingly, however, the suburbs of each of these communities have become very close to each other. As that has happened, providers in each community have followed and established practice sites and free-standing outpatient centers.The payers – The community has a normal looking mix of Commercial, Medicare and Medicaid patients. Because the state’s governor was fiercely against the Affordable Care Act, the Medicaid expansion that happened in other states hasn’t happened here. Thus, the community also has a sizable population without insurance today. As you’d expect, different hospitals see a different mix of these patients. The local health council was able to provide you with the most recent year’s payer mix by hospital – below:Patient visitsCommercialMedicareMedicaidUninsured/Self-payMercy80,500105,80023,00020,700St. Sebastian99,000101,20011,0008,800Gen. Pediatric70,0004,000110,00016,000Gen. University63,00045,00045,00027,000Community Total312,500256,000189,00072,500Reimbursement – the CFO was able to supply you with their best estimate for what various payers are reimbursing for services. In general, the commercial plans are paying 50% of charges, regardless of location, except at General Pediatric. There, the monopoly on pediatric services has allowed them to negotiate rates of 80% of charge, but only for the commercial plans. Medicare currently pays 30% of charges at all hospitals, and Medicaid pays 25% of charges everywhere. Uninsured patients are generally paying 2% of charges.referback to St. Sebastian and the facts laid out in the background reading and Case #1and consider:What products are in this industry vs. part of another distinct group?What is the geographic scope of competition?Identify the participants and segment them. Who are,The buyers and buyer groups?Suppliers and supplier groups?The competitors?The substitutes?The potential entrants?Which of these forces is strong/weak and why?If possible, analyze the industry structure.Why is the level of profitability what it is?Which are the controlling forces for profitability?What are the recent and likely future change in each force, both positive and negative?

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

Read the closing case and post a substantive answer to question below

Read the closing case and post a substantive answer to question belowWhen the former World Bank economist Bingu wa Mutharika became president of the East African nation of Malawi in 2004, it seemed to be the beginning of a new age for one of the world’s poorest countries. In land-locked Malawi, most of the population subsists on less than a dollar a day. Mutharika was their champion. He introduced a subsidy program for fertilizer to help poor farmers and gave them seeds. Agricultural output expanded, and the economy boomed, growing by 7 percent per year between 2005 and 2010. International donors loved him, and aid money started to pour in from the United Kingdom and the United States. By 2011, foreign aid was accounting for more than half of Malawi’s annual budget.In 2009, to no one’s surprise, Mutharika was reelected president. Then things started to fall apart. Mutharika became increasingly dictatorial. He pushed aside the country’s central bankers and ministers to take full con-trol of economic policy. He called himself “Economist in Chief.” Critics at home were harassed and jailed. Independent newspapers were threat-ened. When a cable from the British ambassador describing Mutharika as “autocratic and intolerant of criticism” was leaked, he expelled the British ambassador. Britain responded by freezing aid worth $550 million over four years. When police in mid-2011 killed 20 antigovernment protestors, other aid donors withdrew their support, including most significantly the United States. Mutharika told the donors they could go to hell. To com-pound matters, tobacco sales, which usually accounted for 60 percent of foreign currency revenues, plunged on diminishing international demand and the decreasing quality of the local product, which had been hurt by a persistive drought.By late 2011, Malawi was experiencing a full-blown foreign currency crisis. The International Monetary Fund urged Mutharika to devalue the kwacha, Malawi’s currency, to spur tobacco and tea exports. The kwacha was pegged to the U.S. dollar at 170 kwacha to the dollar. The IMF wanted Malawi to adopt an exchange rate of 280 kwacha to the dollar, which was closer to the black market exchange rate. Mutharika refused, arguing that this would cause price inflation and hurt Malawi’s poor. He also refused to meet with an IMF delegation, saying that the delegates were “too junior.” The IMF put a $79 million loan program it had with Malawi on hold, further exacerbating the foreign currency crisis. Malawi was in a tailspin.In early April 2012, Mutharika had a massive heart attack. He was rushed to the hospital in the capital Lilongwe, but ironically, the medicines that he needed were out of stock—the hospital lacked the foreign cur-rency to buy them! Mutharika died. Despite considerable opposition from Mutharika supporters who wanted his brother to succeed him, Joyce Banda, the vice president, was sworn in as president. Although no one has stated this publicly, it seems clear that intense diplomatic pressure from the United Kingdom and United States persuaded Mutharika’s supporters to relent. Once in power, Banda announced that Malawi would devalue the kwacha by 40 percent. For its part, the IMF unblocked its loan program, while foreign donors, including the UK and United States, stated that they would resume their programs.1. Now that Malawi’s currency has been devalued, what do you think the economic consequences will be? Is this good for the economy?

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.

Explain what is meant by key terms such as ‘LYG’, ‘QALY’ and ‘ICER’Use these terms and the information they represent in a decision-making scenario

Explain what is meant by key terms such as ‘LYG’, ‘QALY’ and ‘ICER’Use these terms and the information they represent in a decision-making scenarioCompare and contrast the demands of effectiveness from different perspectivesScenarioYou are a member of an area prescribing committee (APC) which is reviewing the treatment options for a cancer which is universally rapidly fatal (usually within months) if not treated. For the purposes of this cases study, please assume the following:There is good evidence supporting the effectiveness of three medicines (A, B and C) in improving health outcomes.The treatments are mutually exclusive: there is no evidence that patients are better off switching from one to another.Effectiveness does not depend on patient or disease characteristics.All costs fall within the first year of treatment.Costsvary only according to the drug selected, since staff time, etc. are fixed and are the same requirements for each treatment.The annual budget available for commissioning treatment is US$150,000.The incidence of this cancer in the area covered by your APC is 500 new cases each year.The health economic data are summarized below:Treatment Life Year Gained Health Utility Index (in each year) Cost (per patient)A (Current Practice) 0.3 0.8 $300B 0.4 0.7 $1,500C 0.5 0.5 $500Question 1: Given the available budget of $150,000 per year, how many people could be treated with each option? Please show your calculation and explain briefly.Question 2: Measuring the cost-effectiveness by the incremental cost-effectiveness ratio (ICER), which treatment is the most cost-effective for a hospital use? Please show your calculation and explain briefly.Question 3: From a patient perspective, which treatment is the most effective? Please show your calculation and explain briefly.Question 4: From a society perspective, which treatment generates the greatest health gains given the funds available? Please show your calculation and explain briefly.Question 5: Which treatment would you recommend to the area prescribing committee (APC): A, B or C?

 
Do you need a similar assignment done for you from scratch? We have qualified writers to help you. We assure you an A+ quality paper that is free from plagiarism. Order now for an Amazing Discount!
Use Discount Code "Newclient" for a 15% Discount!

NB: We do not resell papers. Upon ordering, we do an original paper exclusively for you.